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Science 13 February 2004:
Vol. 303. no. 5660, pp. 966 - 968
DOI: 10.1126/science.1094732
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Perspectives

DEVELOPMENT:
Making Sense of the Sensory Lineage

Marianne Bronner-Fraser

Neural crest cells are multipotent stem cell-like precursors that give rise to many different cell types in the developing embryo. In her Perspective, Bronner-Fraser discusses new research (Lee et al.) that identifies the Wnt signaling pathway as the developmental instruction directing neural crest cells to become sensory neurons.

The author is at the California Institute of Technology, Pasadena, CA 91125, USA. E-mail: mbronner{at}caltech.edu

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Imaging neural crest cell dynamics during formation of dorsal root ganglia and sympathetic ganglia.
J. C. Kasemeier-Kulesa, P. M. Kulesa, and F. Lefcort (2005)
Development 132, 235-245
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Science. ISSN 0036-8075 (print), 1095-9203 (online)