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Science 19 December 2003:
Vol. 302. no. 5653, pp. 2074 - 2075
DOI: 10.1126/science.1093165

Perspectives

EVOLUTION:
Climb Every Mountain?

Santiago F. Elena and Rafael Sanjuán

Evolutionary biologists have long argued that adaptation to a particular environmental niche should constrain a population's ability to survive in other niches. In their Perspective, Elena and Sanjuán discuss new evolution experiments with populations of the bacterium Pseudomonas fluorescens (Buckling et al.). These experiments provide evidence that as a bacterial population becomes a niche specialist, it is less able to adapt to other niches.


S. F. Elena is at the Instituto de Biología Molecular y Celular de Plantas, Consejo Superior de Investigaciones Científicas-UPV, 46022 Valencia, Spain. E-mail: sfelena{at}ibmcp.upv.es. R. Sanjuán is at the Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, 46071 Valencia, Spain. E-mail: rafael.sanjuan{at}uv.es

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Natural history as a predictor of protein evolvability.
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Suppression of viral infectivity through lethal defection.
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