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Science 10 October 2003:
Vol. 302. no. 5643, pp. 234 - 235
DOI: 10.1126/science.1090810

Perspectives

CIRCADIAN RHYTHMS:
Liver Regeneration Clocks On

Ueli Schibler

In some simple protozoans and unicellular algae, the cell cycle clock is strongly influenced by the circadian clock, such that mitotic cell division takes place only at certain times of the day. Now, as Schibler reports in his Perspective, new work on regenerating liver cells in mice (Matsuo et al.) reveals that the cell cycle clock of mammalian cells is also under the yoke of the master circadian oscillator.


The author is in the Department of Molecular Biology, University of Geneva, CH-1211 Geneva 4, Switzerland. E-mail: ueli.schibler{at}molbio.unige.ch

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Light-Dependent Regulation of Cell Division in Ostreococcus: Evidence for a Major Transcriptional Input.
M. Moulager, A. Monnier, B. Jesson, R. Bouvet, J. Mosser, C. Schwartz, L. Garnier, F. Corellou, and F.-Y. Bouget (2007)
Plant Physiology 144, 1360-1369
   Abstract »    Full Text »    PDF »
Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging.
D. W. Bartlett and M. E. Davis (2006)
Nucleic Acids Res. 34, 322-333
   Abstract »    Full Text »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)