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Plasmodium falciparum, the most deadly of the human malaria parasites, continues to ravage rural areas of the developing world. As Waters highlights in his Perspective, high-throughput technology is coming to the rescue with the publication here (Le Roch et al.) and elsewhere of the gene expression profiles (transcriptomes) of P. falciparum at different stages of its life cycle. These transcriptome data sets should contribute to identifying new targets for drug and vaccine development.
The author is in the Department of Parasitology, Malaria Group, Leiden University Medical Center, Netherlands. E-mail: Waters{at}lumc.nl
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In Science Magazine
RESEARCH ARTICLES
Karine G. Le Roch, Yingyao Zhou, Peter L. Blair, Muni Grainger, J. Kathleen Moch, J. David Haynes, Patricia De la Vega, Anthony A. Holder, Serge Batalov, Daniel J. Carucci, and Elizabeth A. Winzeler (12 September 2003) Science301 (5639), 1503.
[DOI: 10.1126/science.1087025] |Abstract »|Full Text »|PDF »|Supporting Online Material »
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