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Science 15 August 2003:
Vol. 301. no. 5635, p. 905
DOI: 10.1126/science.301.5635.905a
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News of the Week

NEUROSCIENCE:
Possible Role for Environmental Copper in Alzheimer's Disease

Jean Marx

New results suggest that a combination of low levels of copper ions in drinking water and a high-cholesterol diet somehow promotes an Alzheimer-like pathology in rabbits. Alzheimer's experts caution, however, that much more work will be needed to determine whether the findings apply to human disease.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Copper Binding to the Amyloid-{beta} (A{beta}) Peptide Associated with Alzheimer's Disease: FOLDING, COORDINATION GEOMETRY, pH DEPENDENCE, STOICHIOMETRY, AND AFFINITY OF A{beta}-(1-28): INSIGHTS FROM A RANGE OF COMPLEMENTARY SPECTROSCOPIC TECHNIQUES.
C. D. Syme, R. C. Nadal, S. E. J. Rigby, and J. H. Viles (2004)
J. Biol. Chem. 279, 18169-18177
   Abstract »    Full Text »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)