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Science 8 August 2003:
Vol. 301. no. 5634, p. 757
DOI: 10.1126/science.301.5634.757
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News Focus

NEUROSCIENCE:
Depression Drugs' Powers May Rest on New Neurons

Gretchen Vogel

Blocking neurogenesis in adult mice renders antidepressants ineffective, lending support to a theory that a dearth of newborn neurons contributes to depression. Work described on page 805 provides some of the best evidence to date that changes in neurogenesis might at least partly explain how the disease progresses.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Brain-Derived Neurotrophic Factor in Amygdala-Dependent Learning.
L. M. Rattiner, M. Davis, and K. J. Ressler (2005)
Neuroscientist 11, 323-333
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Science. ISSN 0036-8075 (print), 1095-9203 (online)