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Science 25 July 2003:
Vol. 301. no. 5632, pp. 456 - 457
DOI: 10.1126/science.301.5632.456
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News Focus

GENETICS:
Scientists Dream of 1001 Complex Mice

Gretchen Vogel

OXFORD, U.K.--Geneticists want to create 1000 new lines of inbred mice to help them sort out the genes behind complex diseases such as diabetes and cancer. Skeptics agree that a new approach is needed but caution that the logistics and expense of producing such a resource may outweigh its benefits.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes.
L. Bao, J. L. Peirce, M. Zhou, H. Li, D. Goldowitz, R. W. Williams, L. Lu, and Y. Cui (2007)
Hum. Mol. Genet. 16, 1381-1390
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Genetic and Haplotype Diversity Among Wild-Derived Mouse Inbred Strains.
F. Y. Ideraabdullah, E. de la Casa-Esperon, T. A. Bell, D. A. Detwiler, T. Magnuson, C. Sapienza, and F. P.-M. de Villena (2004)
Genome Res. 14, 1880-1887
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Quantitative genomics: Exploring the genetic architecture of complex trait predisposition.
D. Pomp, M. F. Allan, and S. R. Wesolowski (2004)
J Anim Sci 82, E300-312
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Science. ISSN 0036-8075 (print), 1095-9203 (online)