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MICROBIOLOGY AND EVOLUTION: Modulating Mutation Rates in the Wild
Susan M. Rosenberg and P. J. Hastings
What happens to wild isolates of Escherichia coli bacteria from all walks of life when you put them in a laboratory and starve them? In their Perspective, Rosenberg and Hastings discuss just such a scenario and explain the increased rate of stress-induced mutagenesis--a strategy that may hasten evolution--in starved, aging bacterial colonies derived from wild isolates (Bjedov et al.).
The authors are in the Department of Molecular and Human Genetics, and S. M. Rosenberg is also in the Department of Biochemistry and Molecular Biology and Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA. E-mail: smr{at}bcm.tmc.edu
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RESEARCH ARTICLES
Ivana Bjedov, Olivier Tenaillon, Bénédicte Gérard, Valeria Souza, Erick Denamur, Miroslav Radman, François Taddei, and Ivan Matic (30 May 2003) Science300 (5624), 1404.
[DOI: 10.1126/science.1082240] |Abstract »|Full Text »|PDF »|Supporting Online Material »
