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Science 11 April 2003:
Vol. 300. no. 5617, pp. 225 - 227
DOI: 10.1126/science.300.5617.225
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News of the Week

NUCLEAR TRANSFER:
Misguided Chromosomes Foil Primate Cloning

Gretchen Vogel

While governments debate how to prevent human reproductive cloning, it seems that nature has put a few hurdles of its own in the way. On page 297, a team reports that in rhesus monkeys, cloning robs an embryo of key proteins that allow a cell to divvy up chromosomes and divide properly. Unpublished data from this and other groups suggest that the same problem may also thwart attempts to clone humans.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Fate of centrosomes following somatic cell nuclear transfer (SCNT) in bovine oocytes..
Y. Dai, L. Wang, H. Wang, Y. Liu, N. Li, Q. Lyu, D. L Keefe, D. F Albertini, and L. Liu (2006)
Reproduction 131, 1051-1061
   Abstract »    Full Text »    PDF »
Comment on "Molecular Correlates of Primate Nuclear Transfer Failures".
R. Lanza, Y. Chung, M. D. West, and K. H. S. Campbell (2003)
Science 301, 1482b
   Full Text »    PDF »


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