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Science 14 February 2003:
Vol. 299. no. 5609, p. 995
DOI: 10.1126/science.299.5609.995a

News of the Week

RNA INTERFERENCE:
Mini RNA Molecules Shield Mouse Liver From Hepatitis

Jennifer Couzin

Shooting millions of tiny RNA molecules into a mouse's bloodstream can protect its liver from the ravages of hepatitis, a new study shows. It offers further hope that a novel approach to silencing troublesome genes will become a valuable disease-fighting tool. But the authors and others caution that the therapy must leap many hurdles before it can be safely applied to humans.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)