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Science 10 January 2003:
Vol. 299. no. 5604, pp. 209 - 210
DOI: 10.1126/science.1081345

Perspectives

DEVELOPMENT:
Lymphatics Make the Break

Rakesh K. Jain and Timothy P. Padera

Two vascular networks-the blood system and the lymphatic system-are required for maintaining tissues in a healthy state. In their Perspective, Jain and Padera discuss new work (Abtahian et al.) that identifies two signaling molecules involved in the separation of the blood and lymphatic networks during embryonic development.


The authors are at the Edwin L. Steele Laboratory of Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA. E-mail: jain{at}steele.mgh.harvard.edu

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