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Several gaseous molecules, including nitric oxide and carbon monoxide (CO), are important neurotransmitters. In their Perspective, Boehning and Snyder comment on new work (Dioumet al.) that reveals another important activity for CO, that of modulator of the transcription factor NPAS2, a crucial component of the circadian clock.
The authors are in the Departments of Neuroscience, Pharmacology and Molecular Sciences, and Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. E-mail: ssnyder{at}jhmi.edu
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