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Science 27 September 2002:
Vol. 297. no. 5590, pp. 2185 - 2187
DOI: 10.1126/science.297.5590.2185b
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News of the Week

NEUROSCIENCE:
Drug Find Could Give Ravers the Jitters

Constance Holden

Researchers report on page 2260 that the controversial party drug known as MDMA, or ecstasy, can cause "profound dopaminergic toxicity," possibly explaining some of the drug's reported negative short- and long-term effects. The damage they observed suggests that one all-night "rave" might be enough to induce permanent brain damage and make a person more vulnerable to Parkinson's disease, which is caused by a loss of dopamine-producing neurons.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)