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A year ago came the suprising discovery that animals have perhaps hundreds of micro-RNAs (miRNAs). Now the importance of miRNA in plants and animals is being revealed. In his perspective, Baulcombe describes new work (Llaveet al.; Hutvágner and Zamore) that gives insight into how miRNA and related small RNAs may control processes as diverse as translational arrest, RNA cleavage, and genome rearrangement.
The author is at the Sainsbury Laboratory, John Innes Centre, Norwich NR4 7UH, UK. E-mail: david.baulcombe{at}sainsbury-laboratory.ac.uk
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|Abstract »|Full Text »|PDF »
MicroRNA expression detected by oligonucleotide microarrays: System establishment and expression profiling in human tissues.
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|Abstract »|Full Text »|PDF »
Translation Start Sequences Affect the Efficiency of Silencing of Agrobacterium tumefaciens T-DNA Oncogenes.
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133, 966-977
|Abstract »|Full Text »|PDF »
A microRNA array reveals extensive regulation of microRNAs during brain development.
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RNA
9, 1274-1281
|Abstract »|Full Text »|PDF »
Hairpin RNAs and Retrotransposon LTRs Effect RNAi and Chromatin-Based Gene Silencing.
