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Actin is an important structural element of the cell that is important for cellular processes as diverse as cell division, movement, and intracellular transport. To carry out these different processes, actin is assembled into diverse structures composed of straight or branched filaments. In their Perspective, Chang and Peter discuss new work (Pruyne et al.) that identifies formin proteins as important initiators of the assembly of straight actin filaments.
F. Chang is in the Department of Microbiology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA. E-mail: fc99{at}columbia.edu M. Peter is at the Swiss Institute for Experimental Cancer Research (ISREC), 1066 Epalinges/VD, Switzerland, and the Institute of Biochemistry, CH-8032 Zurich, Switzerland.
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In Science Magazine
REPORTS
David Pruyne, Marie Evangelista, Changsong Yang, Erfei Bi, Sally Zigmond, Anthony Bretscher, and Charles Boone (26 July 2002) Science297 (5581), 612.
[DOI: 10.1126/science.1072309] |Abstract »|Full Text »|PDF »|Supporting Online Material »
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