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Science 24 May 2002:
Vol. 296. no. 5572, pp. 1391 - 1393
DOI: 10.1126/science.296.5572.1391
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News Focus

GENOMICS:
New Mapping Project Splits the Community

Jennifer Couzin

A new type of genomic map, known as the haplotype map, promises to speed the search for elusive genes involved in complex diseases. But to many biologists, it's an untested concept hardly worthy of the $110 million it will consume. Welcome to the haplotype map, a new type of genome map that, depending on where you look, is eliciting exuberance or exasperation.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Genetic Mapping in Human Disease.
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High-throughput discovery of rare human nucleotide polymorphisms by Ecotilling.
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Nucleic Acids Res. 34, e99
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The impact of SNP density on fine-scale patterns of linkage disequilibrium.
X. Ke, S. Hunt, W. Tapper, R. Lawrence, G. Stavrides, J. Ghori, P. Whittaker, A. Collins, A. P. Morris, D. Bentley, et al. (2004)
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Refashioning Race: DNA and the Politics of Health Care.
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A Population Threshold for Functional Polymorphisms.
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Using Multiple Drug Exposure Levels to Optimize Power in Pharmacogenetic Trials.
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J. Clin. Pharmacol. 43, 816-824
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Digital genotyping and haplotyping with polymerase colonies.
R. D. Mitra, V. L. Butty, J. Shendure, B. R. Williams, D. E. Housman, and G. M. Church (2003)
PNAS 100, 5926-5931
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Linkage disequilibrium in human populations.
C. Lonjou, W. Zhang, A. Collins, W. J. Tapper, E. Elahi, N. Maniatis, and N. E. Morton (2003)
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