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Science 10 May 2002:
Vol. 296. no. 5570, pp. 1034 - 1035
DOI: 10.1126/science.1072446
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Perspectives

TRANSCRIPTION:
Chromatin Control--a Place for E2F and Myc to Meet

Nicholas B. La Thangue

The transcription factor E2F switches on target genes during the early G1 phase of the cell cycle. In his Perspective, La Thangue discusses new findings (Ogawa et al.) that reveal the importance of an E2F family member, E2F-6, for silencing genes in quiescent cells in G0 of the cell cycle.

The author is in the Division of Biochemistry and Molecular Biology, Institute of Biomedical and Life Sciences, Davidson Building, University of Glasgow, Glasgow G12 8QQ, UK. E-mail: n.lathangue{at}bio.gla.ac.uk

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Science. ISSN 0036-8075 (print), 1095-9203 (online)