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Science 3 May 2002:
Vol. 296. no. 5569, pp. 823 - 824
DOI: 10.1126/science.296.5569.823a
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News of the Week

ALCOHOLISM RESEARCH:
Stressed Mutant Mice Hit the Bottle

Constance Holden

Some people can drink moderately for years, only to become mired in alcohol after a stressful life event. A new mouse model described on page 931 may help explain why. In the mice, which have been genetically altered to lack a key component of their stress response system, stress apparently acts as a catalyst that makes them--perhaps permanently--more prone to drink.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)