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Science 26 April 2002:
Vol. 296. no. 5568, pp. 689 - 691
DOI: 10.1126/science.296.5568.689

News

Lupus: Mysterious Disease Holds Its Secrets Tight

Eliot Marshall

Something in the lupus patient causes the immune system to go awry and turn its armamentarium of cell-killing forces against the host. Lupus manifests itself in a variety of symptoms, and even professionals have trouble diagnosing it. But an explosion of new data promises to bring lupus research out of the doldrums.

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Gene-Targeted Mice Lacking the Trex1 (DNase III) 3'->5' DNA Exonuclease Develop Inflammatory Myocarditis.
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Autocrine Type I IFN and Contact with Endothelium Promote the Presentation of Influenza A Virus by Monocyte-Derived APC.
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