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Science 19 April 2002:
Vol. 296. no. 5567, pp. 482 - 483
DOI: 10.1126/science.1071206
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Perspectives

PARASITOLOGY:
When the Host Is Smarter Than the Parasite

Daniel E. Goldberg

The wily malaria parasite has become resistant to many affordable frontline antimalarial drugs, and new drug targets are desperately needed. Reporting in a Perspective on new work (Zhang et al.), Goldberg suggests that we look for drug targets among proteins that are shared by the host and parasite but whose synthesis is regulated in a different way.

The author is at the Howard Hughes Medical Institute, Department of Medicine and Department of Molecular Microbiology, Washington University, St. Louis, MO 63130, USA. E-mail: goldberg{at}borcim.wustl.edu

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Science. ISSN 0036-8075 (print), 1095-9203 (online)