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Formation of vesicles carrying secretory proteins depends on the activity of the Golgi, the cell's central protein sorting station. In a Perspective, Bankaitis discusses new findings (Baron and Malhotra) that reveal how protein kinase D, a key molecule required for vesicle formation, is recruited to the Golgi by a lipid called diacylglycerol that is both produced and consumed within this organelle.
The author is in the Department of Cell and Developmental Biology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. E-mail: vytas_bankaitis{at}med.unc.edu
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|Abstract »|Full Text »|PDF »
