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Science 21 December 2001:
Vol. 294. no. 5551, p. 2453
DOI: 10.1126/science.294.5551.2453d
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ScienceScope

The Environmental Protection Agency (EPA)has put on hold plans to use studies in which companies dose people with pesticides while the National Academy of Sciences studies the issue. A 1996 law that requires new safety limits for pesticides on produce prompted industry to expose paid volunteers to chemicals to determine the minimum level at which a toxicant causes effects. The Clinton-era EPA barred using the human data due to ethical concerns, but last month agency officials said they were reviewing some studies (Science, 14 December, p. 2285). Now EPA has shelved the studies until the academy weighs in on whether some human research is "unacceptable," and on how the agency should handle studies that don't follow federal ethics guidelines.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)