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PHYSIOLOGY: A One-Domain Voltage-Gated Sodium Channel in Bacteria
William A. Catterall
Voltage-gated sodium channels are a feature of excitable mammalian cells such as neurons, but have never been found in bacteria. In his Perspective, Catterall discusses the discovery of the first bacterial voltage-gated sodium channel (Ren et al.) and compares the structure and function of this channel with its mammalian counterpart.
The author is in the Department of Pharmacology, University of Washington, Seattle, WA 98195, USA. E-mail: wcatt{at}u.washington.edu
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In Science Magazine
REPORTS
Dejian Ren, Betsy Navarro, Haoxing Xu, Lixia Yue, Qing Shi, and David E. Clapham (14 December 2001) Science294 (5550), 2372.
[DOI: 10.1126/science.1065635] |Abstract »|Full Text »|PDF »
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