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Science 30 November 2001:
Vol. 294. no. 5548, p. 1803
DOI: 10.1126/science.294.5548.1803a
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News of the Week

MOLECULAR IMAGING:
Virus Infects Cell: Live and Uncut

Mary Beckman

On page 1929, a cadre of researchers reports having imaged--in real time--single adeno-associated virus particles entering cells and moving into the nucleus. The closeup view was provided by a technique called single-molecule fluorescence spectroscopy, which may open up gene therapy and antiviral research to highly detailed, blow-by-blow analysis.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)