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Science 5 October 2001:
Vol. 294. no. 5540, pp. 34 - 37
DOI: 10.1126/science.294.5540.34

News Focus

DEVELOPMENT:
New Hints Into the Biological Basis of Autism

Erik Stokstad

Pushed by parent advocates, scientists are unearthing intriguing clues about what causes autism. The evidence seems to point to problems with brain development before birth and through early childhood. Although genetic factors clearly play a major role, a number of other causes and potential cofactors have been postulated, including vaccines, exposure to toxins, infection, and immunologic and metabolic problems. Whatever the causes, a cure for autism remains a faraway prospect, however.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome.
P. Moretti, J. A. Bouwknecht, R. Teague, R. Paylor, and H. Y. Zoghbi (2005)
Hum. Mol. Genet. 14, 205-220
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The Genetics of Autism.
R. Muhle, S. V. Trentacoste, and I. Rapin (2004)
Pediatrics 113, e472-e486
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Science. ISSN 0036-8075 (print), 1095-9203 (online)