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IMMUNOLOGY: Long Live the Mature B Cell--a BAFFling Mystery Resolved
Thomas J. Waldschmidt and Randolph J. Noelle
What determines whether transitional B cells newly emerged from the bone marrow will differentiate further to become mature, long-lived, circulating B lymphocytes? In a Perspective, Waldschmidt and Noelle discuss new findings showing that the TNF family ligand BAFF and its receptor BAFF-R are crucial for selecting transitional B cells into the mature B cell pool (Thompson et al., Schiemann et al.).
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In Science Magazine
REPORTS
Barbara Schiemann, Jennifer L. Gommerman, Kalpit Vora, Teresa G. Cachero, Svetlana Shulga-Morskaya, Max Dobles, Erica Frew, and Martin L. Scott (14 September 2001) Science293 (5537), 2111.
[DOI: 10.1126/science.1061964] |Abstract »|Full Text »|PDF »|Supplemental Data »
REPORTS
Jeffrey S. Thompson, Sarah A. Bixler, Fang Qian, Kalpit Vora, Martin L. Scott, Teresa G. Cachero, Catherine Hession, Pascal Schneider, Irene D. Sizing, Colleen Mullen, Kathy Strauch, Mohammad Zafari, Christopher D. Benjamin, Jurg Tschopp, Jeffrey L. Browning, and Christine Ambrose (14 September 2001) Science293 (5537), 2108.
[DOI: 10.1126/science.1061965] |Abstract »|Full Text »|PDF »|Supplemental Data »
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