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Science 31 August 2001:
Vol. 293. no. 5535, pp. 1602 - 1604
DOI: 10.1126/science.1064981
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Perspectives

BIOMEDICINE:
Clotting Factors Build Blood Vessels

Peter Carmeliet

Recent research suggests that the blood clotting cascade and events during formation of new blood vessels (angiogenesis) are not disconnected processes. In a Perspective, Carmeliet discusses new findings in mouse embryos lacking the thrombin receptor PAR1 that support an intimate connection between blood clotting and angiogenesis (Griffin et al.).

The author is at the University Leuven, Herestraat 49, Leuven, B-3000, Belgium.

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