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Science 13 July 2001:
Vol. 293. no. 5528, p. 237
DOI: 10.1126/science.293.5528.237

News

How DNA Shuffling Works

Jon Cohen

The core technology behind directed molecular evolution is the polymerase chain reaction, the "molecular photocopier" that's used to amplify small amounts of DNA. But scientists at one biotech that is using the technique to produce vaccines have given it a special tweak to produce what they call "DNA shuffling."

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Science. ISSN 0036-8075 (print), 1095-9203 (online)