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Science 8 June 2001:
Vol. 292. no. 5523, pp. 1824 - 1827
DOI: 10.1126/science.292.5523.1824

News Focus

GENETICS:
Can Organisms Speed Their Own Evolution?

Marina Chicurel

Intriguing hints from cell and molecular biologists suggest that in times of stress, organisms may be able to crank up their mutation rates, helping accelerate their own evolution. But evolutionary biologists caution that the evolutionary origins and effects of the newly discovered processes remain uncertain.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Comparative evolutionary genetics of spontaneous mutations affecting fitness in rhabditid nematodes.
C. F. Baer, F. Shaw, C. Steding, M. Baumgartner, A. Hawkins, A. Houppert, N. Mason, M. Reed, K. Simonelic, W. Woodard, et al. (2005)
PNAS 102, 5785-5790
   Abstract »    Full Text »    PDF »
Evolvability is a selectable trait.
D. J. Earl and M. W. Deem (2004)
PNAS 101, 11531-11536
   Abstract »    Full Text »    PDF »
Adaptive Point Mutation and Adaptive Amplification Pathways in the Escherichia coli Lac System: Stress Responses Producing Genetic Change.
S. M. Rosenberg and P. J. Hastings (2004)
J. Bacteriol. 186, 4838-4843
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General Stress Response Regulator RpoS in Adaptive Mutation and Amplification in Escherichia coli.
M.-J. Lombardo, I. Aponyi, and S. M. Rosenberg (2004)
Genetics 166, 669-680
   Abstract »    Full Text »    PDF »
Stress-Induced Mutagenesis in Bacteria.
I. Bjedov, O. Tenaillon, B. Gerard, V. Souza, E. Denamur, M. Radman, F. Taddei, and I. Matic (2003)
Science 300, 1404-1409
   Abstract »    Full Text »    PDF »
The Yolkless Egg and the Evolution of Eutherian Viviparity.
I. Rothchild (2003)
Biol Reprod 68, 337-357
   Abstract »    Full Text »    PDF »



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