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Science 1 June 2001:
Vol. 292. no. 5522, pp. 1665 - 1667
DOI: 10.1126/science.1062045
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Perspectives

MICROBIOLOGY:
Cracking Listeria's Password

B. Brett Finlay

Listeriosis is a serious food-borne bacterial disease that causes death in newborns and the elderly and can induce late-term miscarriages in pregnant women. In a Perspective, Finlay discusses a new mouse model of listeriosis (Lecuit et al.) that mimics the oral infection route of humans and confirms the part played by the bacterial surface protein, internalin, in enabling the bacteria to enter gut epithelial cells of the host.

The author is in the Biotechnology Laboratory, University of British Columbia, Vancouver, V6T 1Z3, British Columbia, Canada. E-mail: bfinlay{at}interchange.ubc.ca

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Science. ISSN 0036-8075 (print), 1095-9203 (online)