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Science 20 April 2001:
Vol. 292. no. 5516, pp. 453 - 454
DOI: 10.1126/science.1060637
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Perspectives

MOLECULAR BIOLOGY:
Invading the Genetic Code

August Böck

All organisms, regardless of where they live or what they do, have but 20 amino acids. This dogma may be about to change, according to Böck in a Perspective. He discusses new results (Wang et al., Doring et al.) describing strategies for supplementing the amino acid repertoire of bacteria with unnatural amino acids, which could be applied to the engineering of completely new proteins.

The author is at der Universitat, Institut fur Genetik und Mikrobiologie, Munich 19 80638, Germany. E-mail: august.boeck{at}lrz.uni-muenchen.de

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Science. ISSN 0036-8075 (print), 1095-9203 (online)