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Carbohydrates have long been avoided by chemists and biologists because of their structural complexity, which makes them difficult to analyze and extremely difficult to synthesize. Now, recent advances in the study of carbohydrate chemistry and biology have put sugar-based drugs on medicine's menu, where they are garnering impressive early reviews. Carbohydrate compounds are currently in clinical trials aimed at fighting everything from inflammation and tissue rejection to hepatitis and cancer.
As a Web supplement to this special issue on Carbohydrates and Glycobiology, Science Online has gathered a page of particularly interesting Web resources in organic chemistry, carbohydrate chemistry, and glycobiology; see www.sciencemag.org/feature/data/carbohydrates.shl.
The editors suggest the following Related Resources on Science sites:
In Science Magazine
INTRODUCTION TO SPECIAL ISSUE
Stella Hurtley, Robert Service, and Phil Szuromi (23 March 2001) Science291 (5512), 2337.
[DOI: 10.1126/science.291.5512.2337] |Summary »
NEWS
Joseph Alper (23 March 2001) Science291 (5512), 2339.
[DOI: 10.1126/science.291.5512.2339] |Summary »|Full Text »
NEWS
Joseph Alper (23 March 2001) Science291 (5512), 2340a.
[DOI: 10.1126/science.291.5512.2340a] |Summary »|Full Text »
NEWS
Robert F. Service (23 March 2001) Science291 (5512), 2340b.
[DOI: 10.1126/science.291.5512.2340b] |Summary »|Full Text »
NEWS
Robert F. Service (23 March 2001) Science291 (5512), 2342.
[DOI: 10.1126/science.291.5512.2342] |Summary »|Full Text »
NEWS
Michael Balter (23 March 2001) Science291 (5512), 2343.
[DOI: 10.1126/science.291.5512.2343] |Summary »|Full Text »
REVIEW
Pamela Sears and Chi-Huey Wong (23 March 2001) Science291 (5512), 2344.
[DOI: 10.1126/science.1058899] |Abstract »|Full Text »|PDF »
REVIEW
Anne Dell and Howard R. Morris (23 March 2001) Science291 (5512), 2351.
[DOI: 10.1126/science.1058890] |Abstract »|Full Text »|PDF »
REVIEW
Carolyn R. Bertozzi and Laura L. Kiessling (23 March 2001) Science291 (5512), 2357.
[DOI: 10.1126/science.1059820] |Abstract »|Full Text »|PDF »
REVIEW
Ari Helenius and Markus Aebi (23 March 2001) Science291 (5512), 2364.
[DOI: 10.1126/science.291.5512.2364] |Abstract »|Full Text »|PDF »
REVIEW
Pauline M. Rudd, Tim Elliott, Peter Cresswell, Ian A. Wilson, and Raymond A. Dwek (23 March 2001) Science291 (5512), 2370.
[DOI: 10.1126/science.291.5512.2370] |Abstract »|Full Text »|PDF »
VIEWPOINT
Lance Wells, Keith Vosseller, and Gerald W. Hart (23 March 2001) Science291 (5512), 2376.
[DOI: 10.1126/science.1058714] |Abstract »|Full Text »|PDF »
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Expression of the Helicobacter pylori adhesin SabA is controlled via phase variation and the ArsRS signal transduction system.
A. C. Goodwin, D. M. Weinberger, C. B. Ford, J. C. Nelson, J. D. Snider, J. D. Hall, C. I. Paules, R. M. Peek Jr, and M. H. Forsyth (2008)
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Update and perspectives on congenital disorders of glycosylation.
