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Science 9 March 2001:
Vol. 291. no. 5510, p. 1872
DOI: 10.1126/science.291.5510.1872
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News of the Week

GENOMES:
Rat Genome Spurs an Unusual Partnership

Eliot Marshall

Last week, the U.S. government plunked down about $60 million in new money to have three labs start sequencing the rat genome. The rat is needed, researchers say, because it has been used more than the mouse for studies of physiology. Nailing down this new genome will be almost as daunting as sequencing the human genome in draft form, however, because rodents also have 3 billion base pairs of DNA.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Voltage-sensitive dye mapping in Langendorff-perfused rat hearts.
A. Nygren, C. Kondo, R. B. Clark, and W. R. Giles (2003)
Am J Physiol Heart Circ Physiol 284, H892-H902
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Insights into Dahl salt-sensitive hypertension revealed by temporal patterns of renal medullary gene expression.
M. Liang, B. Yuan, E. Rute, A. S. Greene, M. Olivier, and A. W. Cowley Jr. (2003)
Physiol Genomics 12, 229-237
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Glass bead purification of plasmid template DNA for high throughput sequencing of mammalian genomes.
D. A. Dederich, G. Okwuonu, T. Garner, A. Denn, A. Sutton, M. Escotto, A. Martindale, O. Delgado, D. M. Muzny, R. A. Gibbs, et al. (2002)
Nucleic Acids Res. 30, e32
   Abstract »    Full Text »    PDF »


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