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Science 25 August 2000:
Vol. 289. no. 5483, pp. 1308 - 1310
DOI: 10.1126/science.289.5483.1308
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Perspectives

NEUROBIOLOGY:
Turning Attraction into Repulsion

Elena Pasquale

A series of molecular cues guide axons as they extend in the embryonic environment. In her Perspective, Pasquale discusses new findings that reveal how signals originating from adhesive contacts between axons and the cells they encounter can repel the axon, causing it to break the adhesive contacts and move away (Hattori et al. and Galko and Tessier-Lavigne).

The author is at the Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. E-mail: elenap{at}burnham.org

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