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Science 18 August 2000:
Vol. 289. no. 5482, pp. 1123 - 1125
DOI: 10.1126/science.289.5482.1123a
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News of the Week

MICROBIOLOGY:
A Weak Link in TB Bacterium Is Found

Laura Helmuth

The secret of the success of Mycobacterium tuberculosis, the pathogen that causes tuberculosis, is that it can linger undetected in the lungs for decades, hiding from the immune system's macrophages that aim to chew it up and spit it out. Now a team of researchers has uncovered a vulnerability in this resilient bug that suggests new ways to starve it out of its bolt-hole.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Mycobacterium tuberculosis (Mtb) isocitrate dehydrogenases show strong B cell response and distinguish vaccinated controls from TB patients.
S. Banerjee, A. Nandyala, R. Podili, V. M. Katoch, K. J. R. Murthy, and S. E. Hasnain (2004)
PNAS 101, 12652-12657
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