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Science 19 May 2000:
Vol. 288. no. 5469, pp. 1146 - 1147
DOI: 10.1126/science.288.5469.1146
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News of the Week

HUMAN GENOME PROJECT:
And the Gene Number Is ...?

Elizabeth Pennisi

COLD SPRING HARBOR, NEW YORK--Biologists have long assumed that the more complex an organism is, the more genes it has. But last week at a meeting here, the generally accepted human gene count of 80,000 to 100,000 took a battering when researchers from Germany, the United States, and France offered revised estimates of the number of genes--all of them well below 50,000. The talks, some of which will be published in the June issue of Nature Genetics, sparked heated debates, with at least one genomicist countering with a new 100,000-plus estimate.

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