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Science 12 May 2000:
Vol. 288. no. 5468, p. 953
DOI: 10.1126/science.288.5468.953
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News Focus

BIOMEDICINE:
Improving Gene Therapy's Tool Kit

Eliot Marshall

More than 4000 patients have been enrolled in gene transfer experiments over the last decade, but until now the research has produced few unambiguous results, mainly due to the difficulty of finding ways of transferring genes into patients. The various viruses that researchers have developed for use as gene therapy "vectors" each have their own risks and advantages.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
The Transduction of Rat Submandibular Glands by an Adenoviral Vector Carrying the Human Growth Hormone Gene is Associated with Limited and Reversible Changes at the Infusion Site.
S. Elmore, L. Lanning, N. Allison, M. Vallant, and A. Nyska (2006)
Toxicol Pathol 34, 385-392
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Science. ISSN 0036-8075 (print), 1095-9203 (online)