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Science 16 April 1999:
Vol. 284. no. 5413, pp. 422 - 425
DOI: 10.1126/science.284.5413.422

News Focus

TISSUE ENGINEERING:
Lab-Grown Organs Begin to Take Shape

Dan Ferber

With the need for transplant organs and tissues growing, researchers are making progress toward developing them artificially, using cultured cells and special polymers. Two months ago a team reported in Nature Biotechnology that it had used tissue engineering to produce new urinary bladders that appeared to work normally in dogs. And on page 489, researchers report growing functioning pig arteries. Less advanced, but showing progress, are efforts to engineer tissues to fill in for failing hearts, livers, and kidneys--organs for which the demand for transplants far outstrips supply.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Tissue Engineering for Reconstruction of the Thumb.
V. R. Hentz and J. Chang (2001)
N. Engl. J. Med. 344, 1547-1548
   Full Text »    PDF »
THE IMPACT OF TISSUE ENGINEERING ON DENTISTRY.
B. J. BAUM and D. J. MOONEY (2000)
J Am Dent Assoc 131, 309-318
   Abstract »    Full Text »    PDF »
Arteries and Bladders Grown and Implanted Successfully in Animals.
(1999)
Journal Watch (General) 1999, 3
   Full Text »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)