NEUROSCIENCE:
Driving the Growth Cone
Pico Caroni
Growth cones are the specialized tips of neuronal axons that make their way through the nervous system in search of a correct target. In his Perspective, Caroni outlines the signaling mechanisms that help steer the growth cone as it moves, and discusses a report by Song et al. in this week's issue that completes our understanding of how the cell is attracted or repulsed by various molecules in its environment.
The author is at the Friedrich Miescher Institute, Maulbeerstrasse 66, CH-4058 Basel, Switzerland. E-mail: caroni{at}fmi.ch