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Science 15 May 1998:
Vol. 280. no. 5366, pp. 1035 - 1036
DOI: 10.1126/science.280.5366.1035
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Research Commentaries

CELL CYCLE:
The Expanding Role of Cell Cycle Regulators

Tyler Jacks and Robert A. Weinberg

The cell cycle is a complex series of protein interactions and enzymatic alterations that governs the orderly division of cells. Jacks and Weinberg summarize new evidence--some of which is presented by Di Cunto et al. in this issue--that the proteins that make up the cell cycle machinery can also have other functions, often in directing the differentiation of cells.

T. Jacks is in the Department of Biology and the Center for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA. R. A. Weinberg is in the Department of Biology and the Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA. E-mail: tjacks{at}mit.edu, weinberg{at}wi.mit.edu

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