Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 2 January 1998:
Vol. 279. no. 5347, pp. 32 - 33
DOI: 10.1126/science.279.5347.32
Prev | Table of Contents | Next

Research News

PHARMACOLOGY:
New Nonopioid Painkiller Shows Promise in Animal Tests

Evelyn Strauss

On page 77, a research team reports promising results in animal tests with a new painkiller called ABT-594, which is related to a chemical originally identified in the skin of a frog. The researchers found that the drug, which apparently acts not through opioid receptors but through a receptor for the neurotransmitter acetylcholine, blocks both acute and chronic pain in rats. What's more, the researchers have seen few signs that ABT-594 is addictive or toxic in animals. Much more work will be needed to determine whether the drug is safe and effective in humans, but safety trials have already begun in Europe.

Read the Full Text

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)