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Science 11 July 1997:
Vol. 277. no. 5323, p. 179
DOI: 10.1126/science.277.5323.179

Research News

PROTEIN STRUCTURE:
Amino Acid Alchemy Transmutes Sheets to Coils

Robert F. Service

A group of biochemists has succeeded in converting the three-dimensional structure of a small protein from one that resembles a sheet with four flat strips lying side by side to another that resembles a collection of four helical telephone cords bunched together. They did so by altering just half the protein's amino acids—an unexpectedly small number.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Dictyostelium discoideum Nuclear Plasmid Ddp5 Is a Chimera Related to the Ddp1 and Ddp2 Plasmid Families.
W. K. Rieben , Jr., C. M. Gonzales, S. T. Gonzales, K. J. Pilkington, H. Kiyosawa, J. E. Hughes, and D. L. Welker (1998)
Genetics 148, 1117-1125
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