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Science 30 May 1997:
Vol. 276. no. 5317, pp. 1324 - 1327
DOI: 10.1126/science.276.5317.1324
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News & Comment

Health Policy:
How Much Pain for Cardiac Gain?

Marcia Barinaga

Since 1993, exercise guidelines promoted by the U.S. government and private organizations have held that moderate activity spread throughout the day is enough to protect against heart disease. But some researchers say that the science doesn't support that conclusion. In their view, sustained vigorous activity--running or aerobic dancing, for example--is required. And this is no mere academic dispute, because inactivity contributes to more than a third of the nearly 500,000 heart-disease-related deaths that occur every year in the United States.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Moderate vs. high exercise intensity: Differential effects on aerobic fitness, cardiomyocyte contractility, and endothelial function.
O. J. Kemi, P. M. Haram, J. P. Loennechen, J.-B. Osnes, T. Skomedal, U. Wisloff, and O. Ellingsen (2005)
Cardiovasc Res 67, 161-172
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Randomised, controlled walking trials in postmenopausal women: the minimum dose to improve aerobic fitness?.
T-M Asikainen, S Miilunpalo, P Oja, M Rinne, M Pasanen, K Uusi-Rasi, and I Vuori (2002)
Br. J. Sports Med. 36, 189-194
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Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise.
H. Pilegaard, G. A. Ordway, B. Saltin, and P. D. Neufer (2000)
Am J Physiol Endocrinol Metab 279, E806-E814
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Exercise as Cardiovascular Therapy • Response.
A. Koller, R. J. Shephard, and G. J. Balady (2000)
Circulation 101 , e164
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Science. ISSN 0036-8075 (print), 1095-9203 (online)