Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.
Active Motif, Inc.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 16 May 1997:
Vol. 276. no. 5315, p. 1023
DOI: 10.1126/science.276.5315.1023
Prev | Table of Contents | Next

News & Comment

Genomics:
A Catalog of Cancer Genes at the Click of a Mouse

Elizabeth Pennisi

An ambitious project that aims at nothing less than a complete catalog of all the genes expressed in cancer cells will debut next month. The Cancer Genome Anatomy Project will classify tumor genes by the type of cancer cell they came from and the degree of the cell's malignancy. The information--available at no charge on the World Wide Web--should help researchers determine how gene expression changes as cancer develops. Ultimately, physicians may be able to base a patient's diagnosis, prognosis, and treatment on the status of a particular tumor's genes, rather than on its appearance under the microscope.

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Identification and Characterization of Prostein, a Novel Prostate-specific Protein.
J. Xu, M. Kalos, J. A. Stolk, E. J. Zasloff, X. Zhang, R. L. Houghton, A. M. Filho, M. Nolasco, R. Badaró, and S. G. Reed (2001)
Cancer Res. 61, 1563-1568
   Abstract »    Full Text »
Molecular Profiling of Clinical Tissue Specimens: Feasibility and Applications.
M. R. Emmert-Buck, R. L. Strausberg, D. B. Krizman, M. F. Bonaldo, R. F. Bonner, D. G. Bostwick, M. R. Brown, K. H. Buetow, R. F. Chuaqui, K. A. Cole, et al. (2000)
J. Mol. Diagn. 2, 60-66
   Full Text »
Molecular Profiling of Clinical Tissue Specimens : Feasibility and Applications.
M. R. Emmert-Buck, R. L. Strausberg, D. B. Krizman, M. F. Bonaldo, R. F. Bonner, D. G. Bostwick, M. R. Brown, K. H. Buetow, R. F. Chuaqui, K. A. Cole, et al. (2000)
Am. J. Pathol. 156, 1109-1115
   Full Text »    PDF »
Identification of Differentially Expressed Genes in Human Prostate Cancer Using Subtraction and Microarray.
J. Xu, J. A. Stolk, X. Zhang, S. J. Silva, R. L. Houghton, M. Matsumura, T. S. Vedvick, K. B. Leslie, R. Badaro, and S. G. Reed (2000)
Cancer Res. 60, 1677-1682
   Abstract »    Full Text »
Heparin/Heparan Sulfate Interacting Protein Gene Expression Is Up-regulated in Human Colorectal Carcinoma and Correlated with Differentiation Status and Metastasis.
Y. Wang, D. Cheong, S. Chan, and S. C. Hooi (1999)
Cancer Res. 59, 2989-2994
   Abstract »    Full Text »    PDF »
Development of new cancer chemoprevention agents: role of pharmacokinetic/pharmacodynamic and intermediate endpoint biomarker monitoring.
R. Lieberman, J. A. Crowell, E. T. Hawk, C. W. Boone, C. C. Sigman, and G. J. Kelloff (1998)
Clin. Chem. 44, 420-427
   Abstract »    Full Text »    PDF »
Discovery of three genes specifically expressed in human prostate by expressed sequence tag database analysis.
G. Vasmatzis, M. Essand, U. Brinkmann, B. Lee, and I. Pastan (1998)
PNAS 95, 300-304
   Abstract »    Full Text »    PDF »


ADVERTISEMENT
Click Me!

ADVERTISEMENT
Click Me!

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)