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Science 25 April 1997:
Vol. 276. no. 5312, pp. 534 - 535
DOI: 10.1126/science.276.5312.534
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Research News

Wade Roush

Seven years ago, researchers announced the identification of a gene called DCC that appeared to be linked to colon cancer. Today, its absence in tumor cells is used as an important diagnostic marker, helping to identify patients who need aggressive treatment. But new studies reported in this week's issue of Nature suggest that DCC plays a key role in neural development. If so, the gene may simply lie close to an unknown tumor suppressor gene and is usually deleted along with it.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Aneuploidy correlated 100% with chemical transformation of Chinese hamster cells.
R. Li, G. Yerganian, P. Duesberg, A. Kraemer, A. Willer, C. Rausch, and R. Hehlmann (1997)
PNAS 94, 14506-14511
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Science. ISSN 0036-8075 (print), 1095-9203 (online)