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Science 28 March 1997:
Vol. 275. no. 5308, pp. 1882 - 0
DOI: 10.1126/science.275.5308.1882
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Research News

Erik Stokstad

An atomic force microscope has made the first movie of an enzyme at work on a DNA molecule. By tapping an ultrafine probe across the sample, the microscope followed an RNA polymerase molecule as it ratcheted down the DNA strand, linking nucleotide bases to create an RNA template for a protein.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)