Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 13 December 1996:
Vol. 274. no. 5294, pp. 1838 - 1840
DOI: 10.1126/science.274.5294.1838
Prev | Table of Contents | Next

Research News

Jean Marx

Two recently identified proteins are moving onto center stage in Alzheimer's disease research: the presenilins, which are mutated in about half of all inherited cases. A recent crop of results implies that these proteins play a role in the cell's internal protein-handling systems. If so, faulty presenilins could contribute to the abnormal buildup of other proteins seen in the brains of Alzheimer's patients.

Read the Full Text


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Slow Degradation of Aggregates of the Alzheimer's Disease Amyloid beta -Protein by Microglial Cells.
D. M. Paresce, H. Chung, and F. R. Maxfield (1997)
J. Biol. Chem. 272, 29390-29397
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)