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Science 11 October 1996:
Vol. 274. no. 5285, pp. 176 - 177
DOI: 10.1126/science.274.5285.176
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Research News

Robert F. Service

After a 12-year effort, scientists have finally captured a detailed image of the business end of the immune system's T cells, which ferret out and mark for destruction cancerous and infected cells. The La Jolla, California-based team has also caught a glimpse of how the T cell latches onto an infected cell. These results, published on page 209, should eventually help drug designers tailor new compounds to promote or, in some cases, block this crucial latching-on process.

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
T Cell Recognition of an Engineered MHC Class I Molecule: Implications for Peptide-Independent Alloreactivity.
V. Jankovic, K. Remus, A. Molano, and J. Nikolich-Zugich (2002)
J. Immunol. 169, 1887-1892
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