Eliot Marshall
While some academic researchers have been signing a pledge not to patent raw DNA sequences, companies that specialize in sequencing DNA--chiefly Incyte Pharmaceuticals of Palo Alto, California, and Human Genome Sciences of Rockville, Maryland--have been channeling data from their automated sequencers into the Patent and Trademark Office (PTO) at a torrential rate. Applications covering more than 400,000 sequences have been filed, and the PTO is seeking help in dealing with the flood.