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Science 1 March 1996:
Vol. 271. no. 5253, pp. 1229 - 1230
DOI: 10.1126/science.271.5253.1229
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Research News

Ingrid Wickelgren

Neurobiologists have long thought that loss of neurons in a particular area of the brain, the CA region of the hippocampus, might account for the ``benign'' memory loss (not Alzheimer's) that sometimes afflicts the aged. But new studies, which were done on human and rat brains and which measure total cell numbers rather than neuronal densities, show little change in the CA region with age. If that is correct, neurobiologists will have to look for a new explanation of why memory may decline during normal aging.


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